Description

4-((1R)-1-Aminoethyl)-2-Bromophenol is a chiral, halogenated phenolic compound featuring both an aminoethyl and a bromo substituent, making it a versatile and valuable building block in advanced organic synthesis. Its unique stereochemistry and functional group combination are critical for constructing complex molecules with specific three-dimensional architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly for applications requiring precise chiral control.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the chiral center can influence biological activity and environmental selectivity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with tailored optical or electronic properties.
• Chemical Biology Probes: Useful for designing and synthesizing molecular probes to study enzyme mechanisms and biological pathways.

Basic Information

Product Name	4-((1R)-1-Aminoethyl)-2-Bromophenol
CAS No.	1213957-83-5
Molecular Formula	C8H10BrNO
Molecular Weight	216.08 g/mol
Synonyms	(R)-4-(1-Aminoethyl)-2-bromophenol; 2-Bromo-4-[(1R)-1-aminoethyl]phenol; 4-[(1R)-1-Aminoethyl]-2-bromophenol; (1R)-1-(4-Hydroxy-3-bromophenyl)ethanamine; (R)-1-(3-Bromo-4-hydroxyphenyl)ethylamine; 1213957-83-5; (R)-4-(1-Aminoethyl)-2-bromophenol hydrochloride (salt form)
EINECS	Contact for details

Quality Control

Every batch of 4-((1R)-1-Aminoethyl)-2-Bromophenol is manufactured under strict quality management systems. We employ advanced analytical techniques, including chiral HPLC, NMR, and mass spectrometry, to ensure identity, purity, and enantiomeric excess meet the high standards required for research and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.