Description

(3R)-3-Amino-3-[3-(Trifluoromethyl)Phenyl]Propan-1-Ol is a high-purity chiral amino alcohol building block of significant interest in advanced organic synthesis. Its core value lies in the trifluoromethylphenyl group, which imparts unique electronic and steric properties critical for modulating the biological activity and physicochemical profile of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly where stereochemistry and fluorine substitution are key design parameters. CAS No. 1213882-28-0.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, especially in central nervous system (CNS) and oncology research.
• Agrochemical Development: Used in creating advanced herbicides, fungicides, and insecticides where the CF3 group enhances lipophilicity and metabolic stability.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, such as oxazolidinone or other N,O-chelating systems.
• Peptidomimetics Research: Incorporated into peptide backbones to create analogs with improved bioavailability and resistance to enzymatic degradation.
• Material Science: Potential monomer or additive for specialty polymers where fluorine content can alter surface properties and chemical resistance.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme mechanisms and protein-ligand interactions.

Basic Information

Product Name	(3R)-3-Amino-3-[3-(Trifluoromethyl)Phenyl]Propan-1-Ol
CAS No.	1213882-28-0
Molecular Formula	C10H12F3NO
Molecular Weight	219.20 g/mol
Synonyms	(R)-3-Amino-3-(3-(trifluoromethyl)phenyl)propan-1-ol; (3R)-3-Amino-3-(3-trifluoromethylphenyl)-1-propanol; 1-Propanol, 3-amino-3-[3-(trifluoromethyl)phenyl]-, (3R)-; (R)-3-Amino-1-(3-(trifluoromethyl)phenyl)propan-3-ol; 3-Amino-3-(3-trifluoromethylphenyl)propan-1-ol (R-enantiomer); (R)-3-Amino-3-(α,α,α-trifluoro-m-tolyl)propan-1-ol
EINECS	Contact for details

Quality Control

Our (3R)-3-Amino-3-[3-(Trifluoromethyl)Phenyl]Propan-1-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity determination by HPLC, to ensure compliance with exacting research and pharmaceutical intermediate standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary to prevent moisture uptake and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.