Description

(2S)-2-Amino-2-[3,5-Bis(tert-Butyl)Phenyl]Ethan-1-Ol is a chiral amino alcohol derivative featuring a sterically hindered 3,5-di-tert-butylphenyl group. This compound matters as a sophisticated building block and chiral ligand or resolving agent in asymmetric synthesis, offering high selectivity due to its bulky substituents. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials where precise stereochemical control is critical.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, particularly for central nervous system (CNS) and cardiovascular targets.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands used in metal-catalyzed asymmetric reactions such as hydrogenation, alkylation, and epoxidation.
• Chiral Resolution Agent: Utilized for the separation of racemic mixtures of carboxylic acids or other acidic compounds via diastereomeric salt formation.
• Agrochemical Synthesis: Building block for creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Material Science Research: Used in the development of chiral polymers, liquid crystals, and molecular recognition systems.
• Academic & Industrial R&D: A valuable tool compound for methodological development in organic and medicinal chemistry laboratories.

Basic Information

Item	Detail
Product Name	(2S)-2-Amino-2-[3,5-Bis(tert-Butyl)Phenyl]Ethan-1-Ol
CAS No.	1213667-87-8
Molecular Formula	C16H27NO
Molecular Weight	249.39 g/mol
Synonyms	(S)-2-Amino-2-(3,5-di-tert-butylphenyl)ethanol; (S)-1-(3,5-Di-tert-butylphenyl)-2-aminoethanol; (2S)-2-Amino-2-(3,5-bis(1,1-dimethylethyl)phenyl)ethanol; (S)-3,5-Di-tert-butylphenylglycinol; Amino alcohol 1213667-87-8; (S)-ATPE; (S)-DTB-PG
EINECS	Contact for details

Quality Control

Our (2S)-2-Amino-2-[3,5-Bis(tert-Butyl)Phenyl]Ethan-1-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting R&D and production standards. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.