Description

D-Phenyl-Ds-Alanine-n-T-Boc is a deuterated, Boc-protected amino acid derivative of significant importance in advanced research and development. This compound is specifically engineered for applications requiring isotopic labeling, offering enhanced stability and analytical precision. It is a critical building block for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly in the synthesis of peptides for drug discovery, metabolic studies, and analytical method development.

Application

• Pharmaceutical Research & Development: As a key deuterium-labeled intermediate in the synthesis of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).
• Metabolic & Pharmacokinetic Studies: Used as an internal standard or tracer in mass spectrometry (MS) and liquid chromatography-mass spectrometry (LC-MS) for accurate quantification and metabolic pathway analysis.
• Proteomics & Biochemistry: Employed in the study of protein structure, function, and dynamics through stable isotope labeling techniques.
• Analytical Chemistry: Serves as a high-purity reference standard for method validation and calibration in analytical laboratories.
• Isotope-Labeled Compound Synthesis: A fundamental precursor for creating more complex deuterated molecules for a wide range of scientific investigations.

Basic Information

Product Name	D-Phenyl-Ds-Alanine-n-T-Boc
CAS No.	1213661-19-8
Molecular Formula	C₁₄H₁₀D₅NO₄
Molecular Weight	~268.33 g/mol (Contact for exact details)
Synonyms	(R)-2-((tert-Butoxycarbonyl)amino)-3-phenylpropanoic-3,3,3-d3 acid; Boc-D-Phenylalanine-d5; N-Boc-D-Phenylalanine-3,3,3-d3; tert-Butyl (R)-(3,3,3-d3)-1-oxo-1-phenylpropan-2-ylcarbamate; Deuterated Boc-D-Phenylalanine; D-Phe(d5)-OH·Boc; N-(tert-Butoxycarbonyl)-D-phenylalanine-3,3,3-d3
EINECS	Contact for details

Quality Control

Our D-Phenyl-Ds-Alanine-n-T-Boc is produced under strict quality management systems to ensure batch-to-batch consistency and high isotopic purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm chemical and isotopic identity, purity, and absence of critical impurities. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under dry, inert conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98 atom % D
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.