Description

(1S)-6-Bromo-1,2,3,4-Tetrahydronaphthalen-1-Amine is a high-purity chiral amine building block of significant interest in advanced organic synthesis. Its value lies in its stereochemically defined structure, which is crucial for creating enantiomerically pure compounds with specific biological activity. This product is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug discovery.
• Asymmetric Synthesis: Used as a building block for constructing complex, enantiomerically pure molecules via reactions like reductive amination or nucleophilic substitution.
• Ligand and Catalyst Development: Employed in the synthesis of novel chiral ligands or organocatalysts for stereoselective transformations.
• Agrochemical Research: Acts as a precursor in the development of new, potentially more selective pesticides and herbicides.
• Material Science: Investigated for incorporation into specialty polymers or advanced organic materials requiring specific optical or electronic properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and for scaling up synthetic routes in process chemistry.

Basic Information

Product Name	(1S)-6-Bromo-1,2,3,4-Tetrahydronaphthalen-1-Amine
CAS No.	1213547-18-2
Molecular Formula	C10H12BrN
Molecular Weight	226.11 g/mol
Synonyms	(1S)-6-Bromo-1,2,3,4-tetrahydro-1-naphthalenamine; (1S)-6-Bromo-1,2,3,4-tetrahydronaphthalen-1-ylamine; (S)-6-Bromo-1,2,3,4-tetrahydronaphthalen-1-amine; 6-Bromo-1,2,3,4-tetrahydronaphthalen-1-amine (S-enantiomer); (1S)-6-Bromo-1-amino-1,2,3,4-tetrahydronaphthalene; (S)-1-Amino-6-bromo-1,2,3,4-tetrahydronaphthalene
EINECS	Contact for details

Quality Control

Our (1S)-6-Bromo-1,2,3,4-Tetrahydronaphthalen-1-Amine is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and NMR for structural confirmation, to ensure compliance with exacting research and development standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and chiral excess is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.