Description

(S)-1-(Indolin-7-Yl)Propan-1-Amine Dihydrochloride is a high-purity chiral amine derivative, specifically the dihydrochloride salt of the (S)-enantiomer. This compound serves as a critical pharmaceutical intermediate and building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of central nervous system (CNS) therapeutics and other specialized drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex molecules targeting neurological pathways.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in studies exploring new catalytic methodologies.
• Medicinal Chemistry & Drug Discovery: Employed in structure-activity relationship (SAR) studies and lead optimization programs.
• Reference Standard: Used as an analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Research: Investigated for its interaction with biological targets such as receptors and enzymes.

Basic Information

Item	Details
Product Name	(S)-1-(Indolin-7-Yl)Propan-1-Amine Dihydrochloride
CAS No.	1213481-13-0
Molecular Formula	C11H16N2 · 2HCl
Molecular Weight	265.18 g/mol
Synonyms	(S)-1-(2,3-Dihydro-1H-indol-7-yl)propan-1-amine dihydrochloride; (S)-1-(Indolin-7-yl)propan-1-amine hydrochloride (1:2); 1H-Indole-1-propanamine, 2,3-dihydro-7-, (1S)-, hydrochloride (1:2); (S)-7-(1-Aminopropyl)indoline dihydrochloride; (S)-1-(7-Indolinyl)propylamine dihydrochloride
EINECS	Contact for details

Quality Control

Our (S)-1-(Indolin-7-Yl)Propan-1-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral purity analysis, and identification by spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.