Description

(3S)-3-Aminoindane-5-Carboxylic Acid is a chiral, non-proteinogenic amino acid derivative featuring a fused indane ring system. This compound serves as a critical pharmaceutical intermediate and chiral building block for the synthesis of complex bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets.
• Peptidomimetics & Constrained Peptide Design: Used to introduce conformational rigidity and specific stereochemistry into peptide backbones to enhance stability and biological activity.
• Ligand Synthesis for Catalysis: Serves as a precursor for chiral ligands used in asymmetric synthesis and catalysis.
• Chemical Biology Research: Employed as a molecular probe or building block in studying enzyme-substrate interactions and protein function.
• Development of Diagnostic Agents: Potential use in creating labeled compounds for imaging and diagnostic applications.
• Academic & Industrial R&D: Fundamental research in organic chemistry and medicinal chemistry for developing new synthetic methodologies.

Basic Information

Product Name	(3S)-3-Aminoindane-5-Carboxylic Acid
CAS No.	1213460-70-8
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	(3S)-3-Amino-2,3-dihydro-1H-indene-5-carboxylic acid; (S)-3-Aminoindane-5-carboxylic acid; 5-Carboxy-(3S)-aminoindane; (S)-5-Carboxy-3-aminoindane; 1H-Indene-5-carboxylic acid, 3-amino-2,3-dihydro-, (3S)-; (3S)-3-Amino-1H-indene-5-carboxylic acid; (S)-AIC; (3S)-AIC
EINECS	Contact for details

Quality Control

Our (3S)-3-Aminoindane-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and chiral purity, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.