Description

(1S)-1-(4-Bromo-2-Thienyl)Ethylamine is a high-purity chiral amine building block of significant importance in modern synthetic chemistry. Its value lies in its unique molecular structure, featuring a brominated thiophene ring and a stereogenic center, which makes it a versatile intermediate for constructing complex, biologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the synthesis of advanced pesticides and herbicides, where the bromothiophene moiety can impart specific biological activity and stability.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to achieve high enantioselectivity.
• Material Science Research: Employed in the development of organic semiconductors and conductive polymers due to the electron-rich thiophene unit.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for studying biological mechanisms and target engagement.

Basic Information

Product Name	(1S)-1-(4-Bromo-2-Thienyl)Ethylamine
CAS No.	1213382-91-2
Molecular Formula	C6H8BrNS
Molecular Weight	206.10 g/mol
Synonyms	(S)-1-(4-Bromo-2-thienyl)ethanamine; (1S)-1-(4-Bromo-2-thienyl)ethanamine; (S)-1-(4-Bromothiophen-2-yl)ethylamine; (S)-4-Bromo-α-methyl-2-thiopheneethanamine; (S)-(-)-1-(4-Bromo-2-thienyl)ethylamine; 4-Bromo-α-methyl-2-thiopheneethanamine (S)-form; (1S)-1-(4-Bromo-thiophen-2-yl)-ethylamine
EINECS	Contact for details

Quality Control

Our (1S)-1-(4-Bromo-2-Thienyl)Ethylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), enantiomeric excess (typically >99% ee), and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.