Description

(S)-5,6,7,8-Tetrahydro-Isoquinolin-8-Ylamine CAS NO 1213172-32-7 is a high-purity chiral amine building block of significant importance in modern synthetic chemistry. Its value lies in its role as a key intermediate for constructing complex molecules with specific stereochemistry, which is critical for biological activity. This compound is primarily needed by pharmaceutical R&D and fine chemical synthesis teams for applications in drug discovery and the development of advanced materials.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology therapeutic areas.
• Asymmetric Synthesis: Serves as a versatile building block in catalytic asymmetric reactions to introduce stereocenters into target molecules.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands and organocatalysts for enantioselective transformations.
• Agrochemical Research: Employed in the synthesis of novel, biologically active compounds for crop protection.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic chemistry and for creating compound libraries for high-throughput screening.

Basic Information

Product Name	(S)-5,6,7,8-Tetrahydro-Isoquinolin-8-Ylamine
CAS No.	1213172-32-7
Molecular Formula	C9H12N2
Molecular Weight	148.21 g/mol
Synonyms	(8S)-5,6,7,8-Tetrahydroisoquinolin-8-amine; (S)-8-Amino-5,6,7,8-tetrahydroisoquinoline; (S)-5,6,7,8-Tetrahydro-8-isoquinolinamine; (S)-THIQ-8-amine; (S)-Aminotetrahydroisoquinoline; (S)-8-Aminotetrahydroisoquinoline; (S)-8-ATIQ
EINECS	Contact for details

Quality Control

Our (S)-5,6,7,8-Tetrahydro-Isoquinolin-8-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.