Description

(2R)-2-Amino-2-[4-(Trifluoromethoxy)Phenyl]Ethan-1-Ol is a high-purity chiral amino alcohol building block, essential for the synthesis of advanced pharmaceutical intermediates and fine chemicals. Its core value lies in the trifluoromethoxy group, which imparts unique metabolic stability and lipophilicity to target molecules, making it a critical component in modern drug discovery. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of central nervous system (CNS) drugs, enzyme inhibitors, and receptor modulators.
• Agrochemical Research: Building block for novel herbicides, fungicides, and insecticides where the trifluoromethoxy moiety enhances biological activity.
• Ligand Synthesis: Precursor for chiral ligands and catalysts used in asymmetric synthesis and homogeneous catalysis.
• Peptidomimetics: Incorporation into peptide backbones to improve stability and bioavailability of therapeutic peptides.
• Material Science: Monomer for specialty polymers and advanced materials requiring specific optical or chemical properties.
• Academic & Contract Research: Valuable reagent for methodological studies in organic and medicinal chemistry within universities and CROs.

Basic Information

Product Name	(2R)-2-Amino-2-[4-(Trifluoromethoxy)Phenyl]Ethan-1-Ol
CAS No.	1213138-76-1
Molecular Formula	C9H10F3NO2
Molecular Weight	221.18 g/mol
Synonyms	(R)-2-Amino-2-(4-(trifluoromethoxy)phenyl)ethanol; (2R)-2-Amino-2-(4-trifluoromethoxyphenyl)ethanol; (R)-1-(4-Trifluoromethoxyphenyl)-2-aminoethanol; (R)-2-Amino-1-[4-(trifluoromethoxy)phenyl]ethanol; 4-(Trifluoromethoxy)-D-phenylglycinol; (R)-4-(Trifluoromethoxy)phenylglycinol; (R)-α-Amino-4-(trifluoromethoxy)benzyl alcohol
EINECS	Contact for details

Quality Control

Our (2R)-2-Amino-2-[4-(Trifluoromethoxy)Phenyl]Ethan-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.