Description

3-((2S)-2-Piperidyl)Thiophene is a high-purity chiral building block featuring a thiophene ring linked to a (S)-configured piperidine moiety. This specific stereochemistry makes it a critical intermediate for the research and development of novel pharmaceuticals, particularly in the areas of central nervous system (CNS) and metabolic disease therapies. It is primarily utilized by medicinal chemists and process development scientists in pharmaceutical R&D and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates targeting neurological receptors.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis.
• Chemical Biology Research: Serves as a scaffold for developing molecular probes to study biological pathways.
• Agrochemical Research: Investigated as a building block for novel active ingredients with specific stereochemical requirements.
• Material Science: Potential precursor for specialty polymers or organic electronic materials due to the conjugated thiophene system.

Basic Information

Product Name	3-((2S)-2-Piperidyl)Thiophene
CAS No.	1213017-20-9
Molecular Formula	C9H13NS
Molecular Weight	167.27 g/mol
Synonyms	(S)-3-(Piperidin-2-yl)thiophene; 3-[(2S)-2-Piperidinyl]thiophene; 3-(2S-Piperidin-2-yl)thiophene; 2-Thienyl-(S)-2-piperidine; (S)-2-(Thiophen-3-yl)piperidine; 1213017-20-9; Thiophene, 3-[(2S)-2-piperidinyl]-
EINECS	Contact for details

Quality Control

Our 3-((2S)-2-Piperidyl)Thiophene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) providing purity, enantiomeric excess, and impurity profiles is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.