Description

((3Ar,7Ar)-Octahydro-1H-Isoindol-3A-Yl)Methanol Hcl is a high-purity, advanced pharmaceutical intermediate with a complex, conformationally locked bicyclic structure. This compound is of significant value for its role as a key chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and antiviral therapeutics. It is essential for research institutions and pharmaceutical manufacturers engaged in process development and the production of high-value, complex molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates targeting neurological disorders.
• API Development: Used in research and process chemistry for constructing complex molecular scaffolds in active pharmaceutical ingredients.
• Asymmetric Synthesis: Serves as a valuable starting material or intermediate in stereoselective chemical reactions due to its rigid, defined stereochemistry.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs in drug discovery.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	((3Ar,7Ar)-Octahydro-1H-Isoindol-3A-Yl)Methanol Hcl
CAS No.	1212106-97-2
Molecular Formula	C9H18ClNO
Molecular Weight	191.70 g/mol
Synonyms	(3aR,7aR)-Octahydro-1H-isoindol-3a-ylmethanol hydrochloride; (3aR,7aR)-Octahydro-2H-isoindol-3a-ylmethanol HCl; (3aR,7aR)-Octahydroisoindol-3a-ylmethanol hydrochloride; (3aR,7aR)-3a-(Hydroxymethyl)octahydro-1H-isoindole hydrochloride; (3aR,7aR)-3a-(Hydroxymethyl)octahydroisoindole HCl; (3aR,7aR)-Octahydro-1H-isoindole-3a-methanol hydrochloride; (3aR,7aR)-Octahydro-2H-isoindole-3a-methanol HCl
EINECS	Contact for details

Quality Control

Our ((3Ar,7Ar)-Octahydro-1H-Isoindol-3A-Yl)Methanol Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and cGMP manufacturing. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.