Description

3-(Endo-9-Fluorenylmethoxycarbonylamino)Bicyclo[2.2.1]Hept-5-Ene-2-Endo-Carboxylic Acid is a specialized, high-purity building block designed for advanced organic synthesis and pharmaceutical research. This compound is valued for its unique norbornene-derived bicyclic structure, which serves as a versatile scaffold for constructing complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications requiring precise stereochemical control and functional group compatibility.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates with complex, constrained ring systems.
• Peptide Mimetics & Conjugation: Serves as a protected amino acid derivative for the synthesis of peptide analogs and for the site-specific bioconjugation of payloads in drug delivery systems.
• Polymer & Material Science: Acts as a functional monomer for ring-opening metathesis polymerization (ROMP) to create specialty polymers with tailored thermal and mechanical properties.
• Chemical Biology Probes: Used to create labeled or tagged molecular probes for studying biological interactions and pathways, leveraging the Fmoc-protected amine for further derivatization.
• Asymmetric Catalysis Ligand Precursor: Provides a rigid, chiral backbone for the development of novel ligands used in asymmetric synthesis and catalysis.
• Agrochemical Research: Employed in the synthesis of novel crop protection agents that benefit from its stereodefined, bicyclic framework.

Basic Information

Product Name	3-(Endo-9-Fluorenylmethoxycarbonylamino)Bicyclo[2.2.1]Hept-5-Ene-2-Endo-Carboxylic Acid
CAS No.	1212066-63-1
Molecular Formula	C24H23NO4
Molecular Weight	389.45 g/mol
Synonyms	Fmoc-3-amino-2-norbornene-2-carboxylic acid (endo); 3-[(9H-Fluoren-9-ylmethoxy)carbonylamino]bicyclo[2.2.1]hept-5-ene-2-carboxylic acid; 3-(Fmoc-amino)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid; N-Fmoc-3-aminonorborn-5-ene-2-carboxylic acid; 3-endo-(Fmoc-amino)-5-norbornene-2-endo-carboxylic acid; Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (1R,2S,3R,4S)-; (1R,2S,3R,4S)-3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 3-(Endo-9-Fluorenylmethoxycarbonylamino)Bicyclo[2.2.1]Hept-5-Ene-2-Endo-Carboxylic Acid adheres to stringent quality management systems to ensure batch-to-batch consistency and high purity for research and development. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and should be handled in a well-ventilated area. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.