Description

1-(1,2,3,4-Tetrahydroisoquinolin-6-Yl)Ethanone Hydrochloride is a high-purity organic salt compound, serving as a critical advanced pharmaceutical intermediate and a versatile building block in medicinal chemistry. Its value lies in enabling the synthesis of complex molecules with potential therapeutic applications, requiring stringent quality control for reliable research and development outcomes. This product is essential for pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new active pharmaceutical ingredients (APIs), particularly within the fields of central nervous system (CNS) and cardiovascular drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially those targeting neurological and cardiovascular pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Serves as a building block in the synthesis of complex APIs containing the tetrahydroisoquinoline pharmacophore.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Academic & Industrial R&D: Facilitates organic synthesis research in universities and industrial settings for developing new heterocyclic compounds.
• Pre-clinical Studies: Used in the preparation of compounds for pharmacological screening and pre-clinical evaluation.

Basic Information

Product Name	1-(1,2,3,4-Tetrahydroisoquinolin-6-Yl)Ethanone Hydrochloride
CAS No.	1211876-16-2
Molecular Formula	C11H14ClNO
Molecular Weight	211.69 g/mol
Synonyms	6-Acetyl-1,2,3,4-tetrahydroisoquinoline hydrochloride; 1-(1,2,3,4-Tetrahydro-6-isoquinolinyl)ethanone hydrochloride; 6-Acetyl-1,2,3,4-tetrahydroisoquinoline HCl; 6-Acetyl-THIQ hydrochloride; Ethanone, 1-(1,2,3,4-tetrahydro-6-isoquinolinyl)-, hydrochloride; 1-(6-Tetrahydroisoquinolinyl)ethanone hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(1,2,3,4-Tetrahydroisoquinolin-6-Yl)Ethanone Hydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request, supporting compliance with cGMP and other relevant pharmaceutical industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.