Description

3-Amino-6-Bromo-1H-Indole-2-Carboxylicacidethylester is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its versatile reactivity, offering both a bromo substituent for cross-coupling reactions and an amino group for further functionalization, making it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex indole-based drug candidates, particularly for oncology and central nervous system (CNS) targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the indole scaffold.
• Material Science: Serves as a building block for organic semiconductors, dyes, and photochromic materials due to its electron-rich indole core and modifiable functional groups.
• Chemical Biology & Proteomics: Employed as a scaffold for designing enzyme inhibitors, fluorescent probes, and molecular tags.
• Academic & Contract Research: Essential for methodological development in organic chemistry, including studies on palladium-catalyzed cross-coupling and heterocyclic chemistry.

Basic Information

Product Name	3-Amino-6-Bromo-1H-Indole-2-Carboxylicacidethylester
CAS No.	1211661-21-0
Molecular Formula	C11H11BrN2O2
Molecular Weight	283.12 g/mol
Synonyms	Ethyl 3-Amino-6-bromo-1H-indole-2-carboxylate; 6-Bromo-3-amino-1H-indole-2-carboxylic acid ethyl ester; 3-Amino-6-bromoindole-2-carboxylic acid ethyl ester; 1H-Indole-2-carboxylic acid, 3-amino-6-bromo-, ethyl ester; 1211661-21-0; AI3-52015; AKOS040759181; ZINC000253910777; SCHEMBL21806227.
EINECS	Contact for details

Quality Control

Our 3-Amino-6-Bromo-1H-Indole-2-Carboxylicacidethylester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.