Description

tert-Butyl Octahydro-1H-Pyrrolo[3,2-B]Pyridine-1-Carboxylate is a protected bicyclic amine derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile nitrogen-containing scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This high-purity building block is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides requiring specific nitrogen-containing heterocyclic structures.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme function and biological pathways.
• Material Science Research: Intermediate for synthesizing specialty polymers and functional materials with tailored properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	tert-Butyl Octahydro-1H-Pyrrolo[3,2-B]Pyridine-1-Carboxylate
CAS No.	1211586-14-9
Molecular Formula	C12H21NO2
Molecular Weight	211.30 g/mol
Synonyms	1-Boc-Octahydro-1H-Pyrrolo[3,2-b]pyridine; 1-(tert-Butoxycarbonyl)octahydro-1H-pyrrolo[3,2-b]pyridine; tert-Butyl 1,2,3,3a,4,5,6,7-Octahydro-1H-pyrrolo[3,2-b]pyridine-1-carboxylate; 1H-Pyrrolo[3,2-b]pyridine-1-carboxylic acid, octahydro-, 1,1-dimethylethyl ester; Boc-Octahydro-1H-Pyrrolo[3,2-b]pyridine; 1-N-Boc-Octahydro-1H-Pyrrolo[3,2-b]pyridine; 1-Boc-Octahydro-pyrrolo[3,2-b]pyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl Octahydro-1H-Pyrrolo[3,2-B]Pyridine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full analytical data are provided for every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.