Description

1-Chloro-6-Formylisoquinoline, also known as 1-Chloro-6-Formyl-2-Azanaphthalene, is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of a reactive formyl group and a chloro-substituted isoquinoline scaffold, enabling precise molecular construction for complex targets. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinases, receptors, and enzymes where the isoquinoline core is pharmacologically relevant.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating specialized chelating ligands, organocatalysts, and metal-organic frameworks (MOFs).
• Material Science: Employed in the development of organic semiconductors, fluorescent dyes, and photoactive materials due to its conjugated π-system.
• Chemical Biology Probes: Utilized to build molecular probes for studying biological processes and protein interactions.
• Academic & Contract Research: A vital reagent for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	1-Chloro-6-Formylisoquinoline
CAS No.	1211528-19-6
Molecular Formula	C₁₀H₆ClNO
Molecular Weight	191.61 g/mol
Synonyms	1-Chloro-6-formyl-2-azanaphthalene; 1-Chloro-6-formylisoquinoline; 6-Formyl-1-chloroisoquinoline; Isoquinoline-6-carboxaldehyde, 1-chloro-; 1-Chloroisoquinoline-6-carbaldehyde; 1211528-19-6
EINECS	Contact for details

Quality Control

Our 1-Chloro-6-Formylisoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) that include data from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.