Description

2-Methyl-1H-Indole-5-Thiol is a specialized sulfur-containing indole derivative, a key building block in advanced organic synthesis. Its unique structure, featuring both a methyl-substituted indole core and a reactive thiol group, makes it a valuable precursor for synthesizing complex heterocyclic compounds and functional materials. This high-purity intermediate is essential for research and development in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and ligands.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Material Science Research: Serves as a precursor for functional organic materials, including organic semiconductors and conductive polymers.
• Chemical Biology Probes: Utilized in creating labeled compounds and probes for studying biological systems and enzyme mechanisms.
• Catalyst Ligand Development: Acts as a starting material for synthesizing novel ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Flavor & Fragrance Chemistry: Employed in the research and synthesis of complex sulfur-containing aroma compounds.

Basic Information

Product Name	2-Methyl-1H-Indole-5-Thiol
CAS No.	1210824-73-9
Molecular Formula	C9H9NS
Molecular Weight	163.24 g/mol
Synonyms	5-Mercapto-2-methylindole; 2-Methyl-5-mercaptoindole; 2-Methylindole-5-thiol; 5-Thiol-2-methylindole; 1H-Indole-5-thiol, 2-methyl-; 2-Methyl-1H-indole-5-thiol; 5-Sulfanyl-2-methyl-1H-indole
EINECS	Contact for details

Quality Control

Our 2-Methyl-1H-Indole-5-Thiol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as identity, assay, and impurity profiles. We support custom synthesis and can tailor specifications to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.