Description

7-Chloro-2,5-Bis(trifluoromethyl)benzimidazole is a high-value, multi-functional heterocyclic building block distinguished by its unique halogenated and fluorinated structure. This compound is critical for the synthesis of advanced materials and active pharmaceutical ingredients (APIs) where electronic properties and metabolic stability are paramount. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel molecules with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel drug candidates, particularly for antiviral, anticancer, and anti-inflammatory therapies, where the benzimidazole core and fluorine atoms improve bioavailability and binding affinity.
• Agrochemical Synthesis: Used in the research and production of next-generation pesticides and herbicides, leveraging its structural motifs to enhance potency and environmental stability.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as ligands for catalysts or components in organic light-emitting diodes (OLEDs), due to its electron-deficient aromatic system.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new chemical reactions and synthesizing complex heterocyclic compounds for various high-tech applications.
• Ligand for Catalysis: Can be utilized to develop specialized ligands for transition metal catalysis, facilitating challenging synthetic transformations.

Basic Information

Product Name	7-Chloro-2,5-Bis(trifluoromethyl)benzimidazole
CAS No.	1209789-75-2
Molecular Formula	C9H3ClF6N2
Molecular Weight	288.58 g/mol
Synonyms	7-Chloro-2,5-bis(trifluoromethyl)-1H-benzimidazole; 1H-Benzimidazole, 7-chloro-2,5-bis(trifluoromethyl)-; 1209789-75-2; 7-Chloro-2,5-di(trifluoromethyl)benzimidazole; 2,5-Bis(trifluoromethyl)-7-chlorobenzimidazole
EINECS	Contact for details

Quality Control

Our 7-Chloro-2,5-Bis(trifluoromethyl)benzimidazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.