Description

Methyl 5-Bromo-1,3-thiazole-2-carboxylate is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new thiazole-based derivatives.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, especially those targeting infectious diseases or metabolic disorders.
• Agrochemical Research: Used to develop novel fungicides, herbicides, or insecticides by serving as a core scaffold for bioactive molecules.
• Material Science: Acts as a building block for creating functionalized polymers or organic electronic materials with specific optoelectronic properties.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and other transformations to introduce the 5-bromothiazole moiety into more complex structures.
• Ligand & Catalyst Development: Useful for synthesizing novel nitrogen-sulfur (N,S) containing ligands for metal catalysis.
• Academic & Contract Research: Serves as a valuable reagent for methodological studies and the discovery of new chemical reactions in academic and industrial R&D labs.

Basic Information

Product Name	Methyl 5-Bromo-1,3-thiazole-2-carboxylate
CAS No.	1209458-91-2
Molecular Formula	C5H4BrNO2S
Molecular Weight	222.06 g/mol
Synonyms	5-Bromo-2-(methoxycarbonyl)thiazole; Methyl 5-bromothiazole-2-carboxylate; 2-Carbomethoxy-5-bromothiazole; 5-Bromothiazole-2-carboxylic acid methyl ester; 1,3-Thiazole-2-carboxylic acid, 5-bromo-, methyl ester; 1209458-91-2
EINECS	Contact for details

Quality Control

Our Methyl 5-Bromo-1,3-thiazole-2-carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.