Description

(1S,4S,5S)-4,7,7-Trimethyl-6-Thiabicyclo[3.2.1]Octane is a high-purity, stereochemically defined bicyclic sulfide compound. This specialized intermediate is valued for its unique three-dimensional structure, which is critical for imparting specific stereochemical and electronic properties in advanced synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for applications in asymmetric synthesis, chiral ligand development, and the construction of complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drug candidates.
• Chiral Ligand/ Catalyst Precursor: Used in the development of novel organocatalysts or metal-complexing ligands for asymmetric transformations, enhancing enantioselectivity.
• Agrochemical Synthesis: Employed in the research and production of advanced, stereospecific pesticides and herbicides where the specific spatial orientation of the molecule affects biological activity.
• Flavor & Fragrance Chemistry: Acts as a precursor for synthesizing sulfur-containing terpenoid derivatives with unique organoleptic properties.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific optical or electronic characteristics due to its constrained bicyclic framework.
• Academic & Process Chemistry: Utilized in methodological studies and scale-up process development for complex organic molecule construction.

Basic Information

Product Name	(1S,4S,5S)-4,7,7-Trimethyl-6-Thiabicyclo[3.2.1]Octane
CAS No.	1208985-45-8
Molecular Formula	C10H18S
Molecular Weight	170.31 g/mol
Synonyms	(1S,4S,5S)-4,7,7-Trimethyl-6-thiabicyclo[3.2.1]octane; endo-4,7,7-Trimethyl-6-thiabicyclo[3.2.1]octane; Bicyclo[3.2.1]octane, 4,7,7-trimethyl-6-thia-, (1S,4S,5S)-; 6-Thiabicyclo[3.2.1]octane, 4,7,7-trimethyl-, (1S,4S,5S)-; Chiral Bicyclic Sulfide; (1S,4S,5S)-TMTBO
EINECS	Contact for details

Quality Control

Our (1S,4S,5S)-4,7,7-Trimethyl-6-Thiabicyclo[3.2.1]Octane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC and GC, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.