Description

5-Fluoro-2-Methyl-2H-Indazole is a high-purity, advanced pharmaceutical intermediate and versatile heterocyclic building block. This compound is critical for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor programs. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific indazole-based scaffolds into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of targeted small-molecule drugs, especially kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Agrochemical Development: Serves as a building block for creating novel crop protection agents and herbicides.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and protein functions.
• Material Science Research: Investigated as a precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	5-Fluoro-2-Methyl-2H-Indazole
CAS No.	1208470-64-7
Molecular Formula	C8H7FN2
Molecular Weight	150.15 g/mol
Synonyms	2H-Indazole, 5-fluoro-2-methyl-; 5-Fluoro-2-methylindazole; 2-Methyl-5-fluoro-2H-indazole; 5-Fluoro-2-methyl-1H-indazole; 1208470-64-7; 5-Fluoro-2-methylindazole; 2-Methyl-5-fluoroindazole
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Methyl-2H-Indazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, supporting cGMP and ISO standards for reliable sourcing in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.