Description

5-Bromo-3-Nitro-1H-Pyrazole is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromo and nitro functional groups into pyrazole-based scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and anti-inflammatory agent discovery.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of modern pesticides and herbicides, leveraging its halogen and nitro substituents for bioactivity.
• Material Science Research: Used in the synthesis of functionalized ligands for metal-organic frameworks (MOFs) and advanced polymeric materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Dye & Pigment Intermediate: Acts as a building block for the production of specialized heterocyclic dyes and colorants.

Basic Information

Product Name	5-Bromo-3-Nitro-1H-Pyrazole
CAS No.	1208314-00-4
Molecular Formula	C3H2BrN3O2
Molecular Weight	191.97 g/mol
Synonyms	1H-Pyrazole, 5-bromo-3-nitro-; 3-Nitro-5-bromo-1H-pyrazole; 5-Bromo-3-nitropyrazole; 5-Bromo-3-nitro-1H-pyrazole; 1208314-00-4; 5-Br-3-NO2-1H-pyrazole
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Nitro-1H-Pyrazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.