Description

4-Bromo-2-(Trifluoromethyl)Benzenethiol is a versatile organosulfur building block characterized by its reactive thiol (-SH) group and halogenated aromatic ring. This compound is essential for introducing sulfur-containing motifs and fluorinated aromatic units into complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications such as ligand synthesis, polymer modification, and the creation of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological disorders and cancers.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiol and trifluoromethyl groups.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create chelating ligands for transition metal catalysts used in cross-coupling and other organic transformations.
• Polymer and Material Science: Acts as a monomer or cross-linking agent for synthesizing specialty polymers, liquid crystals, and self-assembled monolayers (SAMs) on surfaces.
• Chemical Research & Development: A valuable reagent for exploring new synthetic pathways, creating chemical libraries for screening, and developing analytical standards.

Basic Information

Product Name	4-Bromo-2-(Trifluoromethyl)Benzenethiol
CAS No.	1208075-10-8
Molecular Formula	C7H4BrF3S
Molecular Weight	257.07 g/mol
Synonyms	4-Bromo-2-(trifluoromethyl)thiophenol; 2-Trifluoromethyl-4-bromobenzenethiol; 4-Bromo-alpha,alpha,α-trifluoro-o-thiocresol; 1-Bromo-4-mercapto-3-(trifluoromethyl)benzene; 4-Bromo-2-trifluoromethylbenzenethiol; 2-(Trifluoromethyl)-4-bromobenzenethiol; 4-Bromo-2-(trifluoromethyl)phenyl mercaptan
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(Trifluoromethyl)Benzenethiol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from oxidizing agents, strong bases, and sources of ignition. Due to its light-sensitive and easily oxidized nature, prolonged exposure to air and light should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.