Description

7-Methoxyquinoline-4-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic organic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery, catalyst development, and the synthesis of functional organic compounds.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl and heterobiaryl structures, common motifs in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, particularly those containing the quinoline scaffold, which is prevalent in compounds with antimalarial, anticancer, and antimicrobial activity.
• Agrochemical Synthesis: Employed in creating advanced crop protection agents and herbicides that require specific, complex heterocyclic frameworks.
• Material Science Research: Acts as a precursor for organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and sensors, due to the tunable electronic properties of the quinoline core.
• Chemical Biology & Probe Development: Useful for synthesizing molecular probes and labeled compounds for biochemical assays and diagnostic applications.
• Catalyst Ligand Preparation: Serves as a starting material for the synthesis of specialized ligands used in homogeneous catalysis.

Basic Information

Product Name	7-Methoxyquinoline-4-Boronic Acid Pinacol Ester
CAS No.	1207894-59-4
Molecular Formula	C₁₇H₂₂BNO₃
Molecular Weight	299.18 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-7-methoxyquinoline; 7-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline; 7-Methoxyquinoline-4-boronic acid, pinacol ester; 7-Methoxy-4-quinolineboronic acid pinacol ester; Quinoline, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-7-methoxy-; 4-Borono-7-methoxyquinoline pinacol ester; 7-Methoxy-4-(pinacolatoboryl)quinoline
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing lot-specific results are available upon request. We adhere to a quality management system to ensure traceability and consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.