Description

1H-Indole-6-Sulfonamide, 5-Bromo-n-[4-Chloro-3-(Trifluoromethyl)Phenyl]-1-(Cyclopropylcarbonyl)-2,3-Dihydro- is a high-purity, advanced pharmaceutical intermediate designed for research and development in modern drug discovery. This compound is valued for its complex molecular architecture, which incorporates halogenated and sulfonamide functional groups, making it a critical building block for synthesizing novel bioactive molecules. It is primarily targeted at medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries working on new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its unique indole-sulfonamide scaffold.
• Biochemical Probe Development: Employed in the design and creation of chemical probes for investigating biological targets and enzyme inhibition.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex organic molecules for clinical trials.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and novel heterocyclic compound research.

Basic Information

Product Name	1H-Indole-6-Sulfonamide, 5-Bromo-n-[4-Chloro-3-(Trifluoromethyl)Phenyl]-1-(Cyclopropylcarbonyl)-2,3-Dihydro-
CAS No.	1207660-00-1
Molecular Formula	C19H15BrClF3N2O3S
Molecular Weight	523.75 g/mol
Synonyms	5-Bromo-N-[4-chloro-3-(trifluoromethyl)phenyl]-1-(cyclopropylcarbonyl)-2,3-dihydro-1H-indole-6-sulfonamide; 1-(Cyclopropylcarbonyl)-5-bromo-N-[4-chloro-3-(trifluoromethyl)phenyl]-2,3-dihydro-1H-indole-6-sulfonamide; 1207660-00-1; UNII-9J8B9V4R6F; 9J8B9V4R6F; AKOS025310923; CS-0446645.
EINECS	Contact for details

Quality Control

Our 1H-Indole-6-Sulfonamide derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.