Description

1-Bromo-7-Fluoro-2-Azanaphthalene is a high-purity halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its dual functionalization, providing distinct reactive sites for the construction of complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its unique halogenated azanaphthalene scaffold.
• Material Science: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its fused ring system.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology: Utilized as a probe or tag in the development of biochemical tools and diagnostic agents.
• Academic & Contract Research: Essential for fundamental research in heterocyclic and organofluorine chemistry at universities and CROs (Contract Research Organizations).

Basic Information

Product Name	1-Bromo-7-Fluoro-2-Azanaphthalene
CAS No.	1207448-24-5
Molecular Formula	C₉H₅BrFN
Molecular Weight	226.05 g/mol
Synonyms	1-Bromo-7-fluoro-2-azanaphthalene; 1-Bromo-7-fluoroquinoline; 7-Fluoro-1-bromoquinoline; Quinoline, 1-bromo-7-fluoro-; 1-Bromo-7-fluoro-1H-quinoline; 1-Bromo-7-fluoroquinoline; 1207448-24-5; 1-Br-7-F-quinoline
EINECS	Contact for details

Quality Control

Our 1-Bromo-7-Fluoro-2-Azanaphthalene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.