Description

1-Boc-4-Formylindoline is a high-purity, advanced pharmaceutical intermediate and versatile synthetic building block. Its value lies in its dual functional groups—a formyl group and a Boc-protected amine—which enable precise and efficient construction of complex molecular architectures, particularly in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries engaged in developing novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of biologically active molecules, including kinase inhibitors and other targeted therapeutics.
• Organic Synthesis Building Block: Used for constructing indoline-based scaffolds and heterocyclic compounds via reactions such as reductive amination and nucleophilic addition.
• Medicinal Chemistry Research: Employed in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its derivatizable aldehyde functionality.
• Agrochemical Development: Serves as a starting material for creating novel crop protection agents and pesticides.
• Material Science Precursor: Potential use in the synthesis of functional organic materials and ligands for catalysis.

Basic Information

Product Name	1-Boc-4-Formylindoline
CAS No.	1207194-48-6
Molecular Formula	C14H17NO3
Molecular Weight	247.29 g/mol
Synonyms	1-Boc-4-formylindoline; 4-Formyl-1-Boc-indoline; tert-Butyl 4-formyl-2,3-dihydro-1H-indole-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-formylindoline; 1-Boc-4-formyl-2,3-dihydroindole; 4-Aldehyde-1-Boc-indoline; 1-N-Boc-4-formylindoline; 1-Boc-indoline-4-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 1-Boc-4-Formylindoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee consistency and support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.