Description

8-Bromo-2-(trifluoromethyl)imidazo[1,2-a]pyridine is a high-value, multi-functional heterocyclic building block characterized by its fused imidazopyridine core and strategically positioned bromo and trifluoromethyl substituents. This compound is essential for medicinal chemistry and advanced materials research, where its unique structure enables the synthesis of novel compounds with tailored properties. It is primarily sought after by pharmaceutical R&D teams and agrochemical innovators for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in creating novel active ingredients for crop protection products, leveraging the bioactivity of the imidazopyridine scaffold.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for OLEDs or charge-transport molecules, due to its electron-deficient aromatic system.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Library Synthesis for High-Throughput Screening: A valuable building block for constructing diverse compound libraries to identify new hits in drug discovery campaigns.
• Fluorinated Compound Synthesis: The trifluoromethyl group makes it a crucial intermediate for introducing fluorine atoms to enhance metabolic stability, lipophilicity, and bioavailability in target molecules.

Basic Information

Product Name	8-Bromo-2-(trifluoromethyl)imidazo[1,2-a]pyridine
CAS No.	1206981-68-1
Molecular Formula	C8H4BrF3N2
Molecular Weight	265.03 g/mol
Synonyms	8-Bromo-2-(trifluoromethyl)imidazo[1,2-a]pyridine; 2-(Trifluoromethyl)-8-bromoimidazo[1,2-a]pyridine; 8-Bromo-2-trifluoromethylimidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 8-bromo-2-(trifluoromethyl)-; 1206981-68-1; 8-Bromo-2-(trifluoromethyl)-imidazo[1,2-a]pyridine
EINECS	Contact for details

Quality Control

Our 8-Bromo-2-(trifluoromethyl)imidazo[1,2-a]pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP and ISO standards ensures reliable supply for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids, strong bases, and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.