Description

Methyl 1-Chloroisoquinoline-5-Carboxylate CAS NO 1206979-27-2 is a high-value, multi-functional heterocyclic building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules, particularly in medicinal chemistry and agrochemical research, due to its reactive chlorinated isoquinoline core. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries to construct novel compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a precursor for creating specialized ligands, catalysts, and organic electronic materials.
• Academic & Contract Research: Essential reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.
• Custom Synthesis: Employed by fine chemical manufacturers for the contract production of complex, customer-specific molecules.

Basic Information

Product Name	Methyl 1-Chloroisoquinoline-5-Carboxylate
CAS No.	1206979-27-2
Molecular Formula	C11H8ClNO2
Molecular Weight	221.64 g/mol
Synonyms	Methyl 1-chloroisoquinoline-5-carboxylate; 1-Chloro-5-(methoxycarbonyl)isoquinoline; 5-Carbomethoxy-1-chloroisoquinoline; Methyl 5-isoquinolinecarboxylate, 1-chloro-; 1-Chloro-5-methoxycarbonylisoquinoline; 1-Chloroisoquinoline-5-carboxylic acid methyl ester; 1206979-27-2
EINECS	Contact for details

Quality Control

Every batch of Methyl 1-Chloroisoquinoline-5-Carboxylate is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.