Description

Methyl 1-Chloroisoquinoline-7-Carboxylate is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, enabling the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce the versatile isoquinoline scaffold into their target molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas, including central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the biological activity of the chlorinated isoquinoline core.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating novel nitrogen-containing ligands for metal catalysis and organocatalysts.
• Material Science: Employed in the research of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its conjugated system.
• Chemical Biology Probe Development: Utilized to build molecular probes for studying enzyme function and biological pathways in academic and industrial research settings.

Basic Information

Product Name	Methyl 1-Chloroisoquinoline-7-Carboxylate
CAS No.	1206975-02-1
Molecular Formula	C11H8ClNO2
Molecular Weight	221.64 g/mol
Synonyms	Methyl 1-chloro-7-isoquinolinecarboxylate; 1-Chloro-7-isoquinolinecarboxylic acid methyl ester; 7-(Methoxycarbonyl)-1-chloroisoquinoline; 1-Chloroisoquinoline-7-carboxylic acid methyl ester; Methyl 1-chloro-7-quinolinecarboxylate (common misnomer); 1-Chloro-7-(methoxycarbonyl)isoquinoline; 1206975-02-1; 1-Chloro-7-carbomethoxyisoquinoline
EINECS	Contact for details

Quality Control

Our Methyl 1-Chloroisoquinoline-7-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture uptake. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.