Description

6-Bromo-5-(2-Fluoro-4-Nitrophenoxy)-1-Methyl-1H-Indazole is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters for its role as a critical building block in modern medicinal chemistry, enabling the development of targeted therapeutic agents. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the discovery and production of novel small-molecule drugs, particularly in oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities (NCEs).
• Oncology Drug Development: Serves as a core scaffold for compounds targeting specific cancer pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for exploratory research in heterocyclic chemistry and drug discovery.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for potential commercial APIs.

Basic Information

Product Name	6-Bromo-5-(2-Fluoro-4-Nitrophenoxy)-1-Methyl-1H-Indazole
CAS No.	1206800-24-9
Molecular Formula	C14H9BrFN3O3
Molecular Weight	366.15 g/mol
Synonyms	6-Bromo-5-(2-fluoro-4-nitrophenoxy)-1-methyl-1H-indazole; 1-Methyl-6-bromo-5-(2-fluoro-4-nitrophenoxy)indazole; 1-Methyl-6-bromo-5-(2-fluoro-4-nitrophenoxy)-1H-indazole; 1206800-24-9; 6-Bromo-5-(2-fluoro-4-nitrophenoxy)-1-methylindazole; 5-(2-Fluoro-4-nitrophenoxy)-6-bromo-1-methyl-1H-indazole
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-(2-Fluoro-4-Nitrophenoxy)-1-Methyl-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.