Description

1-(Phenylsulfonyl)-5-Methoxy-2-Iodo-4-Azaindole is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring a sulfonyl-protected indole core with halogen and methoxy substituents, makes it a critical intermediate for constructing complex pharmacophores. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of targeted small molecule drugs, particularly kinase inhibitors and other enzyme modulators.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides due to its bioactive scaffold.
• Chemical Biology Probe Development: Employed in creating molecular probes to study biological pathways and protein functions.
• Material Science Research: Investigated as a building block for organic electronic materials and advanced polymers.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process optimization for client projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in cross-coupling and heterocyclic chemistry.

Basic Information

Product Name	1-(Phenylsulfonyl)-5-Methoxy-2-Iodo-4-Azaindole
CAS No.	1206181-42-1
Molecular Formula	C14H11IN2O3S
Molecular Weight	414.22 g/mol
Synonyms	5-Methoxy-2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 5-methoxy-2-iodo-1-(phenylsulfonyl)-; 2-Iodo-5-methoxy-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1-(Benzenesulfonyl)-5-methoxy-2-iodo-1H-pyrrolo[2,3-b]pyridine; 4-Azaindole, 1-(phenylsulfonyl)-5-methoxy-2-iodo-; 1-(Phenylsulfonyl)-5-methoxy-2-iodo-7-azaindole
EINECS	Contact for details

Quality Control

Every batch of 1-(Phenylsulfonyl)-5-Methoxy-2-Iodo-4-Azaindole is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed HPLC, NMR, and MS data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.