Description

6-Chloroisoquinolin-3-Amine is a versatile and high-value heterocyclic building block used in advanced organic synthesis. Its core value lies in its bifunctional nature, featuring both a reactive amine group and a halogenated aromatic system, making it a critical intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, including kinase inhibitors, anticancer agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold.
• Material Science Research: Serves as a building block for creating organic ligands, dyes, and photoactive materials for electronic applications.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Academic & Contract Research: A valuable starting material for methodological development in organic chemistry and medicinal chemistry research programs.
• Custom Synthesis & Scale-Up: Available for contract manufacturing organizations (CMOs) requiring reliable, high-purity building blocks for multi-step synthesis projects.

Basic Information

Product Name	6-Chloroisoquinolin-3-Amine
CAS No.	1204701-64-3
Molecular Formula	C9H7ClN2
Molecular Weight	178.62 g/mol
Synonyms	3-Amino-6-chloroisoquinoline; 6-Chloro-3-isoquinolinamine; 6-Chloroisoquinolin-3-ylamine; 6-Chloro-3-aminoisoquinoline; 1204701-64-3; 6-Chloro-isoquinolin-3-ylamine; 6-Chloro-3-isoquinolinamine; 3-Isoquinolinamine, 6-chloro-
EINECS	Contact for details

Quality Control

Our 6-Chloroisoquinolin-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.