Description

Indole--D5-3-Acetamide is a deuterium-labeled analog of indole-3-acetamide, a key intermediate in the biosynthesis of plant auxins. This stable isotope-labeled compound is essential for advanced research and analytical applications requiring high specificity and minimal background interference. It is primarily utilized by pharmaceutical researchers, agrochemical developers, and analytical laboratories engaged in metabolic studies, tracer experiments, and the development of high-precision quantitative methods.

Application

• Internal Standard for Mass Spectrometry: Serves as a critical quantitative reference standard in LC-MS and GC-MS analysis of plant hormones and related metabolites.
• Metabolic Pathway Tracing: Used in deuterium-labeling studies to elucidate biosynthetic pathways and metabolic fate of auxin-related compounds in plants and microorganisms.
• Pharmaceutical Research: Acts as a labeled intermediate in the synthesis of deuterated drug candidates for improved pharmacokinetic studies (DMPK).
• Agrochemical Development: Employed in research on plant growth regulators and the development of novel, more effective agrochemicals.
• Biochemical Research: A tool for investigating the mechanism of action of indole-3-acetic acid (IAA) and its role in plant physiology.
• Quality Control & Method Development: Essential for developing and validating highly accurate analytical methods in compliance with regulatory guidelines.

Basic Information

Product Name	Indole--D5-3-Acetamide
CAS No.	1204700-53-7
Molecular Formula	C10D5H5N2O
Molecular Weight	189.22 g/mol
Synonyms	3-(Acetylamino)-D5-indole; Indole-3-acetamide-D5; 1H-Indole-3-acetamide-2,4,5,6,7-D5; IAA-amide-D5; Deuterated Indole-3-acetamide; [D5]-Indole-3-acetamide; 3-Acetamido-D5-indole; Auxin Biosynthesis Intermediate-D5
EINECS	Contact for details

Quality Control

Every batch of Indole--D5-3-Acetamide is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity to meet the exacting demands of research and analytical applications. Comprehensive testing includes assay, isotopic enrichment (D-content), and identification by spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.