Description

5-Chloro-1-(Phenylsulfonyl)-6-Azaindole is a high-purity, advanced pharmaceutical intermediate belonging to the azaindole class of heterocyclic compounds. Its unique sulfonylated indole structure makes it a critical building block for medicinal chemistry research and the synthesis of novel active pharmaceutical ingredients (APIs). This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for drug discovery programs targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Biology Probes: Serves as a starting material for creating specialized probes to study biological pathways and enzyme functions.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale synthesis of target molecules.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the life sciences sector.

Basic Information

Product Name	5-Chloro-1-(Phenylsulfonyl)-6-Azaindole
CAS No.	1204501-41-6
Molecular Formula	C13H9ClN2O2S
Molecular Weight	292.74 g/mol
Synonyms	1-(Phenylsulfonyl)-5-chloro-1H-pyrrolo[2,3-b]pyridine; 5-Chloro-1H-pyrrolo[2,3-b]pyridine 1-(phenylsulfonyl)-; 5-Chloro-1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine; 5-Chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 5-Chloro-1H-pyrrolo[2,3-b]pyridine, 1-(phenylsulfonyl)-; 1-Benzenesulfonyl-5-chloro-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-1-(Phenylsulfonyl)-6-Azaindole is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical research and development work. A detailed Certificate of Analysis (COA) including HPLC purity, NMR, and MS data is supplied with each shipment to guarantee it meets your specified requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.