Description

4-Bromo-6-Methylisoquinoline is a high-purity halogenated isoquinoline derivative, a critical building block in advanced organic synthesis. Its unique structure makes it an invaluable intermediate for the development of novel pharmaceuticals and functional materials. This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive heterocyclic core.
• Material Science: Serves as a building block for organic light-emitting diodes (OLEDs), liquid crystals, and other advanced electronic materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the bromo-substituted isoquinoline moiety into more complex molecules.
• Ligand & Catalyst Development: Utilized in the preparation of novel ligands for metal catalysts used in asymmetric synthesis.
• Academic & R&D: A valuable reagent for medicinal chemistry programs and exploratory research in organic and heterocyclic chemistry.

Basic Information

Product Name	4-Bromo-6-Methylisoquinoline
CAS No.	1204298-52-1
Molecular Formula	C10H8BrN
Molecular Weight	222.08 g/mol
Synonyms	6-Methyl-4-bromoisoquinoline; 4-Bromo-6-methyl-isoquinoline; Isoquinoline, 4-bromo-6-methyl-; 4-Bromo-6-methylisoquinoline; 4-Bromo-6-methyl-2-azanaphthalene
EINECS	Contact for details

Quality Control

Our 4-Bromo-6-Methylisoquinoline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality management system is designed to meet the stringent requirements of research and development as well as scale-up production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.