Description

2-Piperazin-1-Yl-6-(Trifluoromethoxy)-1,3-Benzothiazole is a high-value, heterocyclic organic compound featuring a benzothiazole core functionalized with piperazine and trifluoromethoxy groups. This molecular architecture makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in oncology, CNS disorders, and anti-infective research.
• Medicinal Chemistry Building Block: Used extensively in high-throughput screening and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, or insecticides, leveraging the biological activity of the benzothiazole scaffold.
• Chemical Biology Probe: Utilized in biochemical assays to study enzyme inhibition or protein-ligand interactions.
• Material Science Research: Investigated as a potential monomer or additive for creating specialty polymers with unique electronic or optical properties.

Basic Information

Product Name	2-Piperazin-1-Yl-6-(Trifluoromethoxy)-1,3-Benzothiazole
CAS No.	1204296-79-6
Molecular Formula	C₁₂H₁₂F₃N₃OS
Molecular Weight	303.31 g/mol
Synonyms	6-(Trifluoromethoxy)-2-(1-piperazinyl)-1,3-benzothiazole; 2-(Piperazin-1-yl)-6-(trifluoromethoxy)benzothiazole; 6-(Trifluoromethoxy)-2-piperazin-1-yl-1,3-benzothiazole; 2-Piperazin-1-yl-6-trifluoromethoxybenzothiazole; Benzothiazole, 2-(1-piperazinyl)-6-(trifluoromethoxy)-; 1204296-79-6; 2-(Piperazin-1-yl)-6-(trifluoromethoxy)benzo[d]thiazole
EINECS	Contact for details

Quality Control

Our 2-Piperazin-1-Yl-6-(Trifluoromethoxy)-1,3-Benzothiazole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can tailor purity grades to meet specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.