Description

4-[2,2-Dideuterio-2-[[1,1-Dideuterio-6-(4-Phenylbutoxy)Hexyl]Amino]-1-Hydroxyethyl]-2-(Hydroxymethyl)Phenol is a deuterated derivative of a phenolic compound, designed for advanced research and development applications where isotopic labeling is critical. This high-purity compound is valued for its use as a stable isotope-labeled internal standard or tracer in analytical and metabolic studies. It is primarily utilized by pharmaceutical researchers, analytical chemists, and contract research organizations (CROs) working in drug discovery, pharmacokinetics, and bioanalytical method development.

Application

• Internal Standard for LC-MS/MS: Used as a deuterium-labeled internal standard in quantitative bioanalysis to ensure accuracy and precision in mass spectrometry-based assays.
• Metabolic Pathway Tracing: Employed in drug metabolism and pharmacokinetics (DMPK) studies to track the distribution and biotransformation of parent compounds.
• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for the calibration and validation of analytical methods in quality control laboratories.
• Isotope Dilution Mass Spectrometry (IDMS): Critical for high-accuracy quantification in clinical research and environmental analysis where maximum precision is required.
• Proteomics and Biomarker Research: Facilitates relative and absolute quantification in complex biological samples.
• Stable Isotope Labeling in Cell Culture (SILAC): Can be adapted for use in advanced proteomic techniques to study protein expression and turnover.

Basic Information

Product Name	4-[2,2-Dideuterio-2-[[1,1-Dideuterio-6-(4-Phenylbutoxy)Hexyl]Amino]-1-Hydroxyethyl]-2-(Hydroxymethyl)Phenol
CAS No.	1204192-41-5
Molecular Formula	C25H34D4N1O4
Molecular Weight	~428.6 g/mol
Synonyms	Deuterated Phenolic Derivative; 4-[2,2-Dideutero-2-[[1,1-Dideutero-6-(4-Phenylbutoxy)Hexyl]Amino]-1-Hydroxyethyl]-2-(Hydroxymethyl)Phenol; D4-Labeled Phenol Derivative; 2-(Hydroxymethyl)-4-[1-hydroxy-2-[[6-(4-phenylbutoxy)hexyl-d4]amino-d2]ethyl]phenol; Stable Isotope-Labeled Internal Standard 1204192-41-5; Deuterium-Labeled Analytical Standard; (D4)-[6-(4-Phenylbutoxy)hexyl]amino Phenol Derivative
EINECS	Contact for details

Quality Control

This high-value compound is manufactured under strict quality control protocols to ensure isotopic purity and chemical integrity. Each batch is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) is provided, detailing parameters such as chemical purity, isotopic enrichment (D-content), and impurity profile. Our quality system is designed to meet the exacting standards of pharmaceutical R&D and analytical reference material production.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.