Description

Methyl 4,4-Dimethyl-1,2,3,4-Tetrahydroisoquinoline-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the tetrahydroisoquinoline class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and cardiovascular disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides due to its complex heterocyclic structure.
• Organic Synthesis Building Block: Serves as a versatile scaffold for constructing more complex molecules in medicinal and process chemistry.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new chemical reactions and catalytic processes.
• Fine Chemical Production: Integral to the manufacture of high-value specialty chemicals and performance materials.

Basic Information

Product Name	Methyl 4,4-Dimethyl-1,2,3,4-Tetrahydroisoquinoline-5-Carboxylate
CAS No.	1203686-88-7
Molecular Formula	C13H17NO2
Molecular Weight	219.28 g/mol
Synonyms	5-Carbomethoxy-4,4-dimethyl-1,2,3,4-tetrahydroisoquinoline; Methyl 4,4-dimethyl-5-isoquinolinecarboxylate; 4,4-Dimethyl-1,2,3,4-tetrahydroisoquinoline-5-carboxylic acid methyl ester; 1,2,3,4-Tetrahydro-4,4-dimethyl-5-isoquinolinecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4,4-Dimethyl-1,2,3,4-Tetrahydroisoquinoline-5-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for pharmaceutical R&D and cGMP intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.