Description

4,4-Dimethyl-1,2,3,4-Tetrahydroisoquinoline-8-Carbonitrile Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a defined molecular structure. This compound matters as a critical building block in the synthesis of complex organic molecules, offering researchers and manufacturers a reliable and consistent starting material. It is primarily needed by pharmaceutical R&D teams and fine chemical producers engaged in developing novel active pharmaceutical ingredients (APIs), particularly within therapeutic areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Organic Synthesis Building Block: Utilized in research laboratories for constructing complex tetrahydroisoquinoline scaffolds, which are prevalent in medicinal chemistry.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in API manufacturing.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and herbicides.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and functional materials.

Basic Information

Product Name	4,4-Dimethyl-1,2,3,4-Tetrahydroisoquinoline-8-Carbonitrile Hydrochloride
CAS No.	1203686-30-9
Molecular Formula	C12H15ClN2
Molecular Weight	222.71 g/mol
Synonyms	8-Cyano-4,4-dimethyl-1,2,3,4-tetrahydroisoquinoline hydrochloride; 4,4-Dimethyl-1,2,3,4-tetrahydroisoquinoline-8-carbonitrile HCl; 4,4-Dimethyl-1,2,3,4-tetrahydro-8-isoquinolinecarbonitrile hydrochloride; 4,4-Dimethyl-1,2,3,4-tetrahydroisoquinolin-8-yl cyanide hydrochloride
EINECS	Contact for details

Quality Control

Our 4,4-Dimethyl-1,2,3,4-Tetrahydroisoquinoline-8-Carbonitrile Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.