Description

7-Fluoro-4,4-Dimethyl-1,2,3,4-Tetrahydroisoquinoline is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, featuring a tetrahydroisoquinoline scaffold with a fluorine substituent and gem-dimethyl groups, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by pharmaceutical and agrochemical R&D organizations seeking to develop new active ingredients with improved metabolic stability, bioavailability, and binding affinity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of specialty polymers and organic electronic materials that require fluorinated aromatic systems.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules to study biological pathways and protein interactions.

Basic Information

Product Name	7-Fluoro-4,4-Dimethyl-1,2,3,4-Tetrahydroisoquinoline
CAS No.	1203685-22-6
Molecular Formula	C11H14FN
Molecular Weight	179.24 g/mol
Synonyms	7-Fluoro-4,4-dimethyl-1,2,3,4-tetrahydroisoquinoline; 4,4-Dimethyl-7-fluoro-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-7-fluoro-4,4-dimethylisoquinoline; 7-Fluoro-4,4-dimethyl-3,4-dihydro-1H-isoquinoline; F-DMTIQ; 7-F-4,4-DMTIQ
EINECS	Contact for details

Quality Control

Our production of 7-Fluoro-4,4-Dimethyl-1,2,3,4-Tetrahydroisoquinoline adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR) to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment. We support development and commercial projects requiring compliance with cGMP, ICH Q7, and other relevant regulatory guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.