Description

Methyl 4,4-Dimethyl-1,2,3,4-Tetrahydroisoquinoline-7-Carboxylate Hydrochloride is a high-purity, advanced pharmaceutical intermediate with significant value in modern synthetic chemistry. This compound is crucial for research and development teams seeking reliable building blocks for complex molecular architectures. It is primarily utilized by pharmaceutical and biotechnology companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex tetrahydroisoquinoline scaffolds and exploring new chemical spaces.
• Precursor for Fine Chemicals: Serves as a starting material or intermediate for manufacturing specialized fine chemicals and high-value agrochemicals.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development, validation, and quality control in pharmaceutical analysis.

Basic Information

Product Name	Methyl 4,4-Dimethyl-1,2,3,4-Tetrahydroisoquinoline-7-Carboxylate Hydrochloride
CAS No.	1203683-65-1
Molecular Formula	C13H17NO2 • HCl
Molecular Weight	255.74 g/mol
Synonyms	7-Carbomethoxy-4,4-dimethyl-1,2,3,4-tetrahydroisoquinoline hydrochloride; Methyl 4,4-dimethyl-3,4-dihydro-1H-isoquinoline-7-carboxylate hydrochloride; 4,4-Dimethyl-1,2,3,4-tetrahydroisoquinoline-7-carboxylic acid methyl ester hydrochloride; 1203683-65-1; 4,4-Dimethyl-7-(methoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline HCl
EINECS	Contact for details

Quality Control

Our Methyl 4,4-Dimethyl-1,2,3,4-Tetrahydroisoquinoline-7-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.