Description

8-Bromo-4,4-Dimethyl-1,2,3,4-Tetrahydroisoquinoline is a high-purity, advanced pharmaceutical intermediate and versatile organic building block. This compound is valued for its unique brominated tetrahydroisoquinoline scaffold, which is crucial for introducing specific molecular complexity and reactivity in synthetic pathways. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of potential drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used as a building block in the creation of novel pesticides and herbicides, leveraging its halogenated heterocyclic structure.
• Organic Synthesis Reagent: Serves as a versatile precursor for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and further functionalization in complex molecule assembly.
• Material Science Research: Investigated for the synthesis of organic ligands, dyes, and photoactive compounds due to its electron-rich aromatic system.
• Academic & R&D: Employed in university and contract research organization (CRO) laboratories for methodological studies and novel compound library generation.

Basic Information

Product Name	8-Bromo-4,4-Dimethyl-1,2,3,4-Tetrahydroisoquinoline
CAS No.	1203683-45-7
Molecular Formula	C11H14BrN
Molecular Weight	240.14 g/mol
Synonyms	8-Bromo-4,4-dimethyl-1,2,3,4-tetrahydroisoquinoline; 4,4-Dimethyl-8-bromo-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-8-bromo-4,4-dimethylisoquinoline; 8-Bromo-4,4-dimethyl-THIQ; 8-Br-4,4-diMe-THIQ
EINECS	Contact for details

Quality Control

Our 8-Bromo-4,4-Dimethyl-1,2,3,4-Tetrahydroisoquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.