Description

5-Bromo-4,4-Dimethyl-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is a high-purity, synthetically valuable organic salt used as a key building block in advanced chemical synthesis. This compound matters for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals, where its specific brominated tetrahydroisoquinoline scaffold is critical. It is primarily needed by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its functionalized tetrahydroisoquinoline core.
• Process Chemistry Development: Serves as a key starting material or intermediate in scaling up synthetic routes for potential APIs.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological targets and pathways.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals beyond pharmaceuticals.

Basic Information

Product Name	5-Bromo-4,4-Dimethyl-1,2,3,4-Tetrahydroisoquinoline Hydrochloride
CAS No.	1203683-41-3
Molecular Formula	C11H15BrN·HCl
Molecular Weight	278.61 g/mol
Synonyms	5-Bromo-4,4-dimethyl-1,2,3,4-tetrahydroisoquinoline HCl; 4,4-Dimethyl-5-bromo-1,2,3,4-tetrahydroisoquinoline hydrochloride; 1,2,3,4-Tetrahydro-5-bromo-4,4-dimethylisoquinoline hydrochloride; 5-Bromo-4,4-dimethyl-3,4-dihydro-1H-isoquinoline hydrochloride; 5-Br-4,4-diMe-THIQ·HCl
EINECS	Contact for details

Quality Control

Our 5-Bromo-4,4-Dimethyl-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccated environment after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.