Description

1,2,3,4-Tetrahydroisoquinoline-5-Carboxylic Acid Hydrochloride is a high-purity, pharmaceutically relevant organic salt used as a critical building block in advanced chemical synthesis. This compound matters for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in medicinal chemistry, process development, and the synthesis of complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates targeting neurological and cardiovascular disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Organic Synthesis: Serves as a versatile precursor for constructing complex tetrahydroisoquinoline-based scaffolds.
• API Development: Employed in the research and process development stages for new active pharmaceutical ingredients.
• Biochemical Research: Used as a reagent in biochemical studies and as a standard for analytical method development.
• Fine Chemical Production: An intermediate in the manufacture of specialty chemicals and advanced materials.

Basic Information

Product Name	1,2,3,4-Tetrahydroisoquinoline-5-Carboxylic Acid Hydrochloride
CAS No.	1203579-50-3
Molecular Formula	C10H12NO2·HCl
Molecular Weight	213.67 g/mol
Synonyms	5-Carboxy-1,2,3,4-tetrahydroisoquinoline hydrochloride; 1,2,3,4-Tetrahydro-5-isoquinolinecarboxylic acid hydrochloride; THIQ-5-COOH·HCl; 1,2,3,4-Tetrahydroisoquinoline-5-carboxylic acid HCl; 5-(Carboxy)-1,2,3,4-tetrahydroisoquinoline hydrochloride; Isoquinoline-5-carboxylic acid, 1,2,3,4-tetrahydro-, hydrochloride
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydroisoquinoline-5-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.