Description

5-Ethynylisoquinoline is a high-value, functionalized heterocyclic building block of significant interest in advanced organic synthesis and materials science. Its core value lies in the unique reactivity of the ethynyl group, which enables efficient cross-coupling and cycloaddition reactions for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty materials industries, where it serves as a key precursor for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of new drug candidates, particularly in kinase inhibitor and anticancer agent research.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides with enhanced efficacy and selectivity.
• Ligand Precursor: Serves as a starting material for synthesizing sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Building Block: Incorporated into the design of organic semiconductors, conductive polymers, and advanced organic light-emitting diodes (OLEDs).
• Click Chemistry Substrate: The terminal alkyne functionality makes it an ideal participant in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and polymer functionalization.
• Academic & R&D: A valuable tool for methodological development in synthetic organic chemistry and exploring new reaction pathways.

Basic Information

Product Name	5-Ethynylisoquinoline
CAS No.	1203579-37-6
Molecular Formula	C11H7N
Molecular Weight	153.18 g/mol
Synonyms	Isoquinoline, 5-ethynyl-; 5-Ethynyl-isoquinoline; 5-Ethynylisoquinoline; 5-Ethynyl-1-azanaphthalene; 5-Ethynyl-1-azaanthracene (informal); 5-Ethynylbenzo[f]quinoline (related structure); 5-(Ethynyl)isoquinoline
EINECS	Contact for details

Quality Control

Every batch of 5-Ethynylisoquinoline is manufactured and tested under strict quality management protocols to ensure consistency and purity for research and scale-up applications. Our products undergo rigorous analytical characterization using techniques such as HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.