Description

4-Bromoisoquinoline-5-Sulfonyl Chloride Hydrochloride is a high-value, multi-functional chemical building block primarily used in advanced organic synthesis. Its core value lies in its dual functionality, serving as a reactive sulfonyl chloride and a halogenated heterocycle, which enables efficient derivatization for creating complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its bromine and sulfonyl chloride groups for structural diversification.
• Material Science: Potential precursor for functional polymers, liquid crystals, or organic electronic materials due to the rigid isoquinoline core.
• Chemical Biology: Acts as a reagent for protein labeling or as a scaffold in probe development, where the sulfonyl chloride can react with amino groups.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses producing specialized fine chemicals for client R&D.

Basic Information

Product Name	4-Bromoisoquinoline-5-Sulfonyl Chloride Hydrochloride
CAS No.	1203176-80-0
Molecular Formula	C9H6BrCl2NO2S
Molecular Weight	351.02 g/mol
Synonyms	4-Bromo-5-isoquinolinesulfonyl chloride hydrochloride; 5-Isoquinolinesulfonyl chloride, 4-bromo-, hydrochloride; 4-Bromoisoquinoline-5-sulfonyl chloride HCl; 4-Bromo-isoquinoline-5-sulfonyl chloride hydrochloride salt; 1203176-80-0; 4-Br-IQ-5-SO2Cl·HCl
EINECS	Contact for details

Quality Control

Every batch of 4-Bromoisoquinoline-5-Sulfonyl Chloride Hydrochloride is produced and tested under strict quality management protocols. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, is performed to verify identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, and custom purity grades are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.