Description

2-(5-Methylisoxazol-3-Yl)But-3-Yn-2-Ol is a high-purity, advanced pharmaceutical intermediate featuring a unique isoxazole-alkyne scaffold. This compound matters as a critical building block for medicinal chemistry research and the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and life sciences industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in areas targeting neurological disorders and inflammation.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its reactive alkyne and heterocyclic motifs.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides and fungicides with specific modes of action.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme function and biological pathways via click chemistry reactions.
• Material Science: Potential monomer or cross-linker for creating specialized polymers with tailored thermal or optical properties.

Basic Information

Product Name	2-(5-Methylisoxazol-3-Yl)But-3-Yn-2-Ol
CAS No.	1202769-66-1
Molecular Formula	C8H9NO2
Molecular Weight	151.16 g/mol
Synonyms	3-Butyn-2-ol, 2-(5-methyl-3-isoxazolyl)-; 2-(5-Methyl-3-isoxazolyl)-3-butyn-2-ol; 2-(5-Methylisoxazol-3-yl)but-3-yn-2-ol; 1202769-66-1; 5-Methyl-3-(1-hydroxy-1-methyl-2-propynyl)isoxazole
EINECS	Contact for details

Quality Control

Our 2-(5-Methylisoxazol-3-Yl)But-3-Yn-2-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full traceability are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.