Description

(5-Fluoro-1H-Indol-2-Yl)Boronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic chemistry. Its value lies in enabling the efficient construction of complex indole-based molecules through reliable cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that incorporate the biologically active 5-fluoroindole scaffold.
• Material Science: Serves as a monomer or functionalization agent in the creation of advanced organic electronic materials and functional polymers.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and activity-based protein profiling (ABPP) reagents to study enzyme function.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of diverse compound libraries for high-throughput screening (HTS) in medicinal chemistry programs.

Basic Information

Product Name	(5-Fluoro-1H-Indol-2-Yl)Boronic Acid
CAS No.	1202709-15-6
Molecular Formula	C8H7BBrFNO2
Molecular Weight	243.86 g/mol
Synonyms	5-Fluoro-1H-indole-2-boronic acid; 5-Fluoro-2-indoleboronic acid; (5-Fluoro-2-indolyl)boronic acid; 2-Borono-5-fluoroindole; 5-Fluoroindole-2-boronic acid; B-(5-Fluoro-1H-indol-2-yl)boronic acid; 1202709-15-6
EINECS	Contact for details

Quality Control

Our (5-Fluoro-1H-Indol-2-Yl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistent performance in cross-coupling reactions. Certificates of Analysis (COA) with full specification data are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) for long-term stability and to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.